CBD for Pets: What Every Pet Owner Should Know

Cannabidiol (CBD), a primary compound found in the cannabis plant, has sparked considerable interest due to its potential therapeutic benefits. The substance is used in a variety of products such as oils and edibles, delivering relaxation and calm effects to humans[1]Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364. … Continue reading. In recent years, the application of CBD has extended to the world of veterinary medicine, prompting discussions about its effects on pets. As this is an emerging field, pet owners should consider several factors before deciding to use CBD for their pets.

The Science Behind CBD

Understanding the effects of CBD necessitates comprehension of its interaction with the body. Both humans and many animals, including dogs and cats, possess an endocannabinoid system (ECS). This complex cell-signaling system is crucial for maintaining homeostasis — the body’s inner equilibrium. The ECS is involved in the regulation of numerous functions, such as sleep, mood, appetite, memory, reproduction, and pain[2]Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular sciences, 19(3), 833. … Continue reading. CBD influences the ECS by inhibiting the absorption of anandamide, a natural cannabinoid associated with pain regulation, thereby increasing its levels in the bloodstream and mitigating the pain a pet may experience.

Potential Benefits of CBD for Pets

Though research on the benefits of CBD in pets is ongoing, preliminary findings and anecdotal evidence indicate that it may deliver several health benefits. These may include anti-inflammatory properties, cardiac benefits, anti-nausea effects, appetite stimulation, anti-anxiety impact, and potential anti-cancer benefits, although no conclusive data supports the latter yet.

A study by Gamble et al. (2018) published in Frontiers in Veterinary Science[3]Gamble, L. J., Boesch, J. M., Frye, C. W., Schwark, W. S., Mann, S., Wolfe, L., … & Wakshlag, J. J. (2018). Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in … Continue reading reported that CBD oil could significantly decrease pain and increase activity in dogs suffering from osteoarthritis. Furthermore, a study by McGrath et al. (2019) in the Journal of the American Veterinary Medical Association[4]McGrath, S., Bartner, L. R., Rao, S., Packer, R. A., & Gustafson, D. L. (2019). Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to … Continue reading noted that CBD could reduce seizure frequency in dogs. These initial findings point towards the possibility that CBD could play a critical role in managing various conditions in pets.

Safety and Risks of CBD for Pets

Although CBD is generally considered safe, it does carry some potential risks. There is a risk of overdosing, leading to adverse effects such as dry mouth, low blood pressure, and drowsiness[5]Huestis, M. A., Solimini, R., Pichini, S., Pacifici, R., Carlier, J., & Busardò, F. P. (2019). Cannabidiol Adverse Effects and Toxicity. Current neuropharmacology, 17(10), 974–989. … Continue reading. Pets might also exhibit altered liver enzyme activity, interfering with the metabolism of some drugs.

Moreover, the FDA does not currently regulate CBD products, leading to significant quality and content variations between products. This lack of regulation could mean that products may not contain the stated amount of CBD or might contain other substances like THC, toxic to dogs and cats. It’s important to check the Certificate of Analysis to make sure that the amount of CBD used is accurate. Most of the major manufacturer’s have current and past data available, so you can check different batches for consistency. If you need help reading a CoA, we have a helpful guide available.

Also, while CBD might help manage symptoms of certain conditions, it should not replace prescribed medication unless a veterinarian suggests it.

Selecting CBD Products for Pets

When selecting a CBD product for pets, it’s crucial to ensure it’s derived from hemp and not marijuana, as hemp-derived CBD typically contains less than 0.3% THC. It’s also essential to choose a product that’s been third-party tested to verify the contents. Pet owners should look for products that have been certified by the National Animal Supplement Council (NASC) for assurance of quality and safety.

Before starting any CBD regimen for a pet, consultation with a veterinarian is necessary. They can provide guidance on whether CBD is right for the pet and suggest suitable dosages based on the pet’s size, weight, and health status.

Conclusion

CBD can potentially offer various health benefits for pets, including anti-inflammatory properties, anxiety reduction, and pain relief. It is essential to consult with a veterinarian before starting a CBD regimen to ensure the safety and health of the pet. As more research is conducted and regulations are established, the role of CBD in pet health will become clearer and safer to navigate.

References

References
1 Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364. https://pubmed.ncbi.nlm.nih.gov/21749363/
2 Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular sciences, 19(3), 833. https://pubmed.ncbi.nlm.nih.gov/29533978/
3 Gamble, L. J., Boesch, J. M., Frye, C. W., Schwark, W. S., Mann, S., Wolfe, L., … & Wakshlag, J. J. (2018). Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs. Frontiers in veterinary science, 5, 165. https://pubmed.ncbi.nlm.nih.gov/30083539/
4 McGrath, S., Bartner, L. R., Rao, S., Packer, R. A., & Gustafson, D. L. (2019). Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy. Journal of the American Veterinary Medical Association, 254(11), 1301–1308. https://pubmed.ncbi.nlm.nih.gov/31067185/
5 Huestis, M. A., Solimini, R., Pichini, S., Pacifici, R., Carlier, J., & Busardò, F. P. (2019). Cannabidiol Adverse Effects and Toxicity. Current neuropharmacology, 17(10), 974–989. https://pubmed.ncbi.nlm.nih.gov/31161980/